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Stratum germinativum

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The stratum germinativum (or basal layer, stratum basale) is the deepest layer of the epidermis, a continuous layer of cells often described as one cell thick, though it may be two to three cells thick in glabrous skin and hyperproliferative epidermis.[1] The basal cells of this layer can be considered the "stem cells" of the epidermis, undifferentiated, proliferating, and creating daughter cells that migrate upward, beginning the process of differentiation.[2]. At any given time, basal keratinocytes (stratum germinativum) is participating in mitosis.

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[edit] References

  1. ^ McGrath, J.A.; Eady, R.A.; Pope, F.M. (2004). Rook's Textbook of Dermatology (Seventh Edition). Blackwell Publishing. Pages 3.7. ISBN 9780632064298.
  2. ^ Marks, James G; Miller, Jeffery (2006). Lookingbill and Marks' Principles of Dermatology (4th ed.). Elsevier Inc. Page 6. ISBN 1-4160-3185-5.
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